Hidden Markov Models 3 6
نویسنده
چکیده
6.1.1 Preface: CpG islands It is known that due to biochemical considerations that CpG, the pair of nocleotides C and G, appearing successively, in this order, along one DNA starnd, is relatively rare in DNA sequences, excluding particular sub-sequences, which are several hundreds of nucleotides long, where the couple CpG is more frequent. These sub-sequences, called CpG islands, are known to appear in the biologically more signi cant parts of the genome. The ability to identify CpG islands in the DNA will therefore help us spot the more signi cant regions of interest along the genome.
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